Minimally clinically significant. If youre receiving the CellCept IV infusion, the typical dosage is 1,000 mg given twice per day. The typical starting dosage for this purpose is 600 mg per square meter (m2) of body surface area (a measure of the size of their body) given twice daily. It isnt known if CellCept can pass into breast milk. If taken with CellCept, these antacids can lower the amount of CellCept in your body. This extra fluid in your body can make it seem like youve gained weight. Other medications that affect this process can slow the breakdown of CellCept in your body. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Tell them about all prescription, over-the-counter, and other drugs you take. This reaction is a natural process that happens in your body when your immune system detects other unknown substances, such as bacteria. CellCept will stay in your system for about 1 week after your last dose. (Skin spots may be discolored, scaly, or crusty.). antacids that contain magnesium and aluminum (CellCept and the antacid should not be taken at the same time). Notes for Consumers: Do not take Mycophenolate with Food unless instructed otherwise. Use of the terms male and female in this article refers to sex assigned at birth. How does blood work, and what problems can occur? The IV infusion should be given within 24 hours of a transplant. However, as soon as youre able to swallow CellCept capsules, tablets, or liquid, your doctor will likely stop giving you the infusion form. CellCept isnt FDA-approved to treat lupus. There are 308 drugs known to interact with Here we look at how these drugs are alike and different. If youre taking a form of CellCept thats swallowed, in most cases you should take it on an empty stomach. Below are the typical doses for preventing organ rejection after a heart, kidney, or liver transplant in adults. stop taking CellCept. CellCept alcohol/food interactions There is 1 alcohol/food interaction with CellCept (mycophenolate mofetil). (Mycophenolate is the active drug in CellCept). The generic is considered to be as safe and effective as the original drug. It alerts doctors and patients about drug effects that may be dangerous. No, you shouldnt donate blood while taking CellCept. A boxed warning is the most serious warning from the FDA. They make your body less likely to reject a transplanted organ. Its also supported by additional data from use in children. However, as soon as CellCept capsules, tablets, or liquid can be swallowed, discontinue the infusion form. A generic drug is an exact copy of the active drug in a brand-name medication. For more information on these side effects, see Side effect details below. * The CellCept IV infusion is used for people who arent able to swallow CellCept capsules, tablets, or liquid. Storage requirements for CellCept vary with each formulation: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, you should still check with your doctor or pharmacist before using any of these products while taking CellCept. Below are examples of off-label uses for CellCept. Common examples are medications that treat high cholesterol, high blood pressure, and migraines. Its not known how many people may have experienced this side effect after taking CellCept in clinical studies. (See. Call your doctor right away if you have serious side effects. Treating scleroderma isnt an FDA-approved use for CellCept. Having symptoms of organ rejection doesnt necessarily mean that your transplant has failed or that youll need another transplant. If you experience weight gain while using CellCept, tell your doctor. There arent any known interactions between CellCept and alcohol. Youll also need to check your insurance plan, as it may only cover one or the other. * CellCept and Prograf have boxed warnings for these side effects. What drugs and food should I avoid while taking Cellcept (Mycophenolate Mofetil (Oral/Injection))? CellCept is meant to be used as a long-term treatment. Both CellCept and Prograf are available as capsules that you swallow and as an intravenous (IV) infusion* (an injection into a vein over a period of time). This is because live vaccines generally require a healthy immune system to be effective. CellCept is indicated for use in combination with other immunosuppressants to help prevent organ rejection after a heart, liver, or kidney transplant. CellCept was compared with azathioprine (Azasan, Imuran) in clinical studies of adults who had a liver transplant. Take Mycophenolate either 1 hour before or 2 hours after eating. There is 1 alcohol/food/lifestyle interaction with CellCept (mycophenolate mofetil). For this reason, your doctor will likely need to prescribe other antibiotics to treat your infection. CellCept decreases blood levels of the hormones in birth control pills that you take by mouth. Avoid soft mold-ripened and blue-veined cheeses such as Brie, Camembert, Roquefort, Stilton, Gorgonzola and Bleu or other soft, unpasteurized cheeses. Each form of CellCept comes in different strengths. Iron is a mineral. CellCept is used to prevent organ rejection in patients who are at least three months of age who have received a liver transplant, a heart transplant, or a kidney transplant. This date is typically 1 year from the date they dispensed the medication. They can discuss ways to lower your risk. Avoid grapefruit unless MD instructs otherwise. These lists contain up to 10 of the most common mild side effects that can occur with each drug, or with both CellCept and Myfortic (when taken individually). CellCept contains the active ingredient mycophenolate mofetil. While outdoors, wear a broad-spectrum sunscreen with a high protection factor. Your pharmacist will mix the medicine before you pick it up from a pharmacy. In this situation, your doctor may give you the CellCept infusion for up to 14 days. In rare cases, taking CellCept can lead to serious infections that cause sepsis (a life threatening response to an infection) or death. Avoid eating raw or undercooked: seafood poultry meats eggs This also includes unpasteurized milk or cheese.. Here are answers to some frequently asked questions about CellCept. (Infections that happen after taking medications that weaken your immune system, such as CellCept, are sometimes called opportunistic infections.) To help prevent organ rejection, dont stop taking CellCept without first discussing the risks with your doctor. Researchers are also looking into other uses. Prograf is available as a generic drug called tacrolimus. CellCept can affect your ability to drive or operate machines. If you and your doctor determine that CellCept is safe and effective for you, youll likely continue taking it for as long as you have your transplanted organ. In this situation, your doctor may give you the CellCept infusion for up to 14 days. However, studies have found both CellCept and Prograf considered to be effective for preventing organ rejection. Talk with your doctor if you have questions about using CellCept for lupus. ), The typical dosage of CellCept for preventing rejection of a kidney transplant is 1,000 mg taken twice per day. . 6 disease interactions, and 1 alcohol/food interaction. These lists dont include all possible side effects that may occur with each drug. Both CellCept and Myfortic are FDA-approved to help prevent organ rejection after a kidney transplant in adults and in children. Organ rejection occurs when your immune system attacks a transplanted organ. Highly clinically significant. A boxed warning is the most serious warning from the FDA. The injectable formulation is also contraindicated in people who have an allergy to Polysorbate 80 (TWEEN). Consult your healthcare professional (e.g.,. Side effects that were more common in children include: For more information on these side effects, see the Mild side effects and Serious side effects sections above. In addition, studies show that people with higher fiber intakes tend to have healthier estrogen levels. There is 1 alcohol/food interaction with CellCept (mycophenolate mofetil). It works by preventing immune cells from multiplying. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Enter other medications to view a detailed report. Specifically, CellCept and Prograf are a type of immunosuppressant called antirejection drugs. The result: too much drug in your body . Isavuconazole, an antifungal medication, is an example of a drug that can affect how CellCept is broken down in the body. Hair loss may also happen after an organ transplant. In this instance, the CellCept infusion can be administered for up to 14 days. CellCept is also available as tablets and as a liquid that you swallow. are pregnant or plan to become pregnant. Highly clinically significant. CellCept can interact with antacids (medications used to relieve heartburn or indigestion) that contain magnesium hydroxide or aluminum hydroxide. However, clinical studies have found some effectiveness when used off-label to treat this condition in adults and in children. If you have a lighter skin tone or a family history of skin cancer, your risk of getting skin cancer while using CellCept may be even higher. CellCept can also make certain forms of birth control less effective. CellCept is available as capsules, tablets, and a liquid that you swallow. CellCept and Myfortic are both brand-name drugs. This is especially true for birth control pills that contain the active drug levonorgestrel. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. (Azathioprine is an antirejection drug, like CellCept.) Cellcept can cause serious side effects, including: Increased risk of loss of a pregnancy (miscarriage) and higher risk of birth defects. Try to take your doses around the same time each day. It is indicated for use in adults and children ages 3 months and older. Take this medication by mouth as directed by your doctor, usually twice daily on an empty stomach, 1 hour before or 2 hours after meals.. Both of these forms are typically taken twice per day. (Cyclosporine is another antirejection drug.). (Organ rejection occurs when the immune system attacks a transplanted organ.). Note: The IV infusion is used for people who cannot swallow CellCept capsules, tablets, or liquid. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Examples of effective birth control include: Males who use CellCept should use effective birth control while taking the drug and for at least 90 days after their last dose. CellCept belongs to a group of drugs called antimetabolite immunosuppressants. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Other interactions can increase side effects or make them more severe. If you have questions about using CellCept with other medications, talk with your doctor. This means taking your dose either 1 hour before eating or 2 hours after eating. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. It is an immunosuppressant drug that tamps down the immune system and helps to prevent organ rejection. To learn more, see the CellCept precautions section below. However, chemotherapy drugs cant tell the difference between healthy cells and cancer cells. It's important to keep taking mycophenolate even if it doesn't seem to be working at first. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Generics tend to cost less than brand-name drugs. CellCept is approved to help prevent organ rejection in children ages 3 months and older after a heart, kidney, or liver transplant, in combination with other immunosuppressants. If you experience a rash while using CellCept, talk with your doctor. CellCept isnt FDA-approved to treat myasthenia gravis (a disease of the nerves and muscles). This card may help lower the cost of the drug for you. Below are examples of these side effects. For this purpose, CellCept is approved for use in children ages 3 months and older. * PPIs are medications used to treat conditions such as heartburn or gastroesophageal reflux disease. If the medicine is broken or is not intact, do not get the powder on your skin or eyes. Different interactions can cause different effects. CellCept may also be used off-label for other conditions, including: If youd like more information on the use of CellCept in treating these conditions, talk with your doctor. (Cholestyramine is a drug used to treat high cholesterol.). The forms of CellCept that are swallowed are all typically taken twice per day. If you have unused medication that has gone past the expiration date, talk with your pharmacist about whether you might still be able to use it. This happens because the immune system doesnt recognize the new organ as part of your body. They can tell you about other medications that may work well for you. * Some may be a better fit for you than others. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. Some medications are cleared from the body through kidney tubules (small tubes in the kidney that filter your blood). CellCept is used with other immunosuppressant medicines containing cyclosporine and corticosteroids. Before using CellCept, be sure to tell your doctor about any other medications youre taking. Tell your doctor right away if you have any signs of infection (see What is the most important information I should know about CellCept?), including any unexpected bruising or bleeding. (Having a stable transplant means you arent experiencing any symptoms of organ rejection. Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Promptly consult your doctor or pharmacist. People who take CellCept have a higher risk of getting skin cancer. CellCept oral suspension contains aspartame (a source of phenylalanine). Phosphate binders are often used in people who have kidney problems and are receiving dialysis. Eat smaller meals. Most people who have had organ transplants take CellCept both right after transplantation and for the long term. Do not use more CellCept than your doctor recommends. Its important to note that pregnancy registry data is self-reported, meaning the results are submitted by people taking the drug. Chemotherapy drugs work by destroying all cells that are growing quickly. After 12 months of treatment: These results were similar to the results observed in adults using CellCept for kidney transplants. The actual price youll pay depends on your insurance plan, your treatment plan, your location, and if applicable, the pharmacy you use. For more information on the possible side effects of CellCept, talk with your doctor or pharmacist. * CellCept and Myfortic have boxed warnings for these side effects. Possible side effects include: 3Heart- CellCept increases the risk of high blood pressure and rapid heart rate. Precautions. If you have questions about using CellCept to help prevent organ rejection, talk with your doctor. CellCept is metabolized (broken down) in the body by a process called glucuronidation. Do not take with food unless your doctor approves. Note: Sex and gender exist on spectrums. *) Talk with your doctor about whether or not your condition is stable enough to take this drug with food. Generally speaking, the higher the dose and the longer the treatment, the greater the changes. If you would like to notify the FDA about a side effect youve had with CellCept, you can do so through MedWatch. CellCept and Myfortic have different FDA-approved uses, but theyre both used to help prevent organ rejection after kidney transplant. CellCept is used with other medicines containing cyclosporine and corticosteroids. CellCept contains the active ingredient mycophenolate mofetil. In a clinical study of children ages 3 months and older, CellCept was given with corticosteroids and cyclosporine. Hair loss isnt a side effect of CellCept thats been reported in clinical studies. However, hair loss is a possible side effect of other drugs that are used with CellCept to help prevent organ rejection, such as tacrolimus (Prograf). Minor multivitamins with minerals mycophenolate mofetil Minor Drug Interaction Information for this minor interaction is available on the professional version. Other symptoms of anemia may include chest pain, shortness of breath, headache, and irregular or fast heart rate. Check with your doctor right away if you have bloody urine, decreased frequency or amount of urine, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, trouble breathing, unusual tiredness or weakness, vomiting, or weight gain. However, if you do have any of these symptoms, tell your doctor right away so they can treat your condition. They make your body less likely to reject a transplanted organ. A change in your diet, medicine, or dosage may be necessary. The most common symptom of anemia is fatigue. They can recommend ways to treat this side effect. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre using CellCept. Your doctor may want to monitor your treatment with CellCept more closely. However, live vaccines could cause infections in people whose immune systems are weakened, including those taking immunosuppressants such as CellCept. A kitchen timer can work, too. A boxed warning is the most serious warning from the FDA. * For this purpose, CellCept is approved for use in children ages 3 months and older. Heres some detail on certain side effects this drug may or may not cause. However, if they become more severe or dont go away, talk with your doctor or pharmacist. You can also refrigerate the liquid at temperatures of 36F to 46F (2C to 8C). In addition to the use listed above, CellCept is also used off-label for other purposes at times. It works by inhibiting the inosine monophosphate dehydrogenase enzyme, preventing B-cell and T-cell lymphocytes from multiplying. All three treatments were given with corticosteroids and cyclosporine. CellCept is also FDA-approved to help prevent organ rejection after a heart or liver transplant in adults and children ages 3 months and older. If you accidentally get the powder or oral suspension on the skin, wash the area well with soap and water. This helps make sure you dont transfer the powder or liquid to a surface that might be touched by someone whos pregnant. If youre taking a form of CellCept thats swallowed, in most cases you should take it on an empty stomach. They also included problems with the esophagus, kidneys, nervous system, and abnormalities of the arms and legs. Sharing this information can help you avoid potential interactions. Some vaccines may not work as well during treatment with CellCept. You should always consult your doctor or another healthcare professional before taking any medication. This can raise your risk for side effects from drugs that are cleared through kidney tubules. The risk of pregnancy loss is highest during the first 3 months of pregnancy. CellCept (mycophenolate mofetil, or MMF) is a common treatment for people who have had organ transplants. Birth control pills may not work as well while you take CellCept, and you could become pregnant. French fries and potato chips are often very high in calories and . Both drugs were given with corticosteroids and cyclosporine (Neoral). Is the ketogenic diet right for autoimmune conditions? Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. CellCept is typically taken twice daily. Tablets should be stored at room temperature (77F/25C) in a tightly sealed container away from light. Tell your doctor right away if you have any signs of depression while using CellCept. This lowers your immune systems ability to attack the newly transplanted organ. These drugs make your body less likely to reject a transplanted organ. However, if you do have any of these symptoms, tell your doctor right away so they can treat your condition. Therefore, this information was not gathered in a clinical study overseen by researchers. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. They can give you tips on how to deal with any side effects that may be bothersome. The use of CellCept and Myfortic in preventing organ rejection after kidney transplant has been directly compared in a clinical study. Call your healthcare provider right away. These serious infections can include: Call your doctor right away if you have any of the following signs and symptoms of infection: SeeWhat are the possible side effects of CellCept?for information about other serious side effects. Whole grains contain more fiber, protein, and micronutrients than refined grains. They can discuss with you the risks and benefits of continuing your CellCept treatment. (Organ rejection occurs when the immune system attacks a transplanted organ. It's recommended that you take the capsule or tablet with food and water, as this can stop you feeling sick and getting stomach pains. To help make sure you dont miss a dose, try using a medication reminder. CellCept is available as a generic drug called mycophenolate mofetil. If you have questions about whether CellCept is right for your child, talk with their doctor. The capsule forms of both drugs are typically taken twice per day. And animal studies dont always indicate what may happen in humans. . Taking CellCept with proton pump inhibitors (PPIs)* can lower the amount of CellCept in your body. Its important to note that your results while using CellCept may vary from those seen in clinical studies. For instance, some interactions can interfere with how well a drug works. Paxlovid (nirmatrelvir/ritonavir) is an oral antiviral medication that's authorized to treat certain people who have mild to moderate COVID-19. Symptoms can include: discoloration, heat, pain, or swelling in the infected area, 27.4% to 39.9% of adults who were given CellCept had an infection, 24.9% to 33.7% of adults using azathioprine had an infection, 37.3% of adults using a placebo had an infection, 0.4% to 1% of adults developed a type of lymphoma (depending on the condition being treated), 1.35% of children developed a type of lymphoma, 1.6% to 4.2% of adults developed skin cancer, 0.7% to 2.1% of adults developed other types of cancer, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, 20.1% of adults who were given CellCept after a heart transplant had depression, 15.2% of adults who were given azathioprine after a heart transplant had depression, loss of interest in activities you once enjoyed, trouble concentrating or making decisions, 26% of adults who used CellCept had a rash, 20.8% of adults who used azathioprine had a rash, 20% to 45% of adults who used CellCept had anemia, 23.6% to 53% of adults who used azathioprine had anemia, 2.4% of adults who used a placebo had anemia, 32% of adults who used CellCept experienced an organ rejection, 35% of adults who used azathioprine experienced an organ rejection, 6.2% of adults who used CellCept required a new heart transplant or died, 11.4% of adults who used azathioprine required a new heart transplant or died, 38.5% of adults who used CellCept experienced an organ rejection, 47.7% of adults who used azathioprine experienced an organ rejection, 14.7% of adults who used CellCept required a new heart transplant or died, 14.6% of adults who used azathioprine required a new heart transplant or died, stopping the study early for any reason other than organ rejection, 30.3% to 38.8% of adults using CellCept experienced treatment failure, 47.6% to 50% of adults using azathioprine experienced treatment failure, 56% of adults using a placebo experienced treatment failure, 2% of children died while receiving CellCept for their kidney transplant, the type of organ transplant youre using CellCept for, capsules, available in one strength of 250 milligrams (mg), tablets, available in one strength of 500 mg, liquid that you swallow, available in one strength of 200 mg per milliliter (mL) of liquid, a maximum dose of 3,000 mg daily or 15 mL of oral suspension daily, a maximum dose of 2,000 mg daily or 10 mL of oral suspension daily, serious inflammatory reaction which may cause fever, joint pain, joint stiffness, and muscle pain, numbness or tingling in your hands and feet, low levels of magnesium and phosphate in your blood, QT prolongation (a change in the electrical activity of your heart), myocardial hypertrophy (a certain heart problem), aluminum hydroxide/magnesium carbonate (Gaviscon), aluminum hydroxide/magnesium hydroxide/simethicone (Mylanta), fluoroquinolones, such as levofloxacin (Levaquin), capsules, tablets, and liquid that you swallow. Stance of the medicines you take work, and what problems can occur * the CellCept for. Down the immune system attacks a transplanted organ. ) and updates and patients about drug effects that may well! Occur with this drug may or may not work as well during treatment with CellCept, and micronutrients than grains... By someone whos pregnant may work well for you than others information for this purpose, CellCept is with. Raise your risk for side effects of CellCept thats swallowed, in most you!, see the CellCept IV infusion, the higher the dose and the longer treatment! And you could become pregnant works by inhibiting the inosine monophosphate dehydrogenase enzyme, preventing and... Here we look at how these drugs are alike and different 1 week after your last dose would! Can discuss with you the CellCept infusion for up to 14 days knowledge. Considered to be as safe and effective as the original drug are swallowed are typically. 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